Association of ABCB1 T-129C polymorphism and multiple myeloma risk in Polish population
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation of FAS A-670G Polymorphism and Risk of Uterine Leiomyoma in a Southeast Iranian Population
Background: Uterine leiomyoma (UL) is a benign tumor of uterine smooth muscle that affects women in reproductive ages. FAS has an important role in initial stages of apoptosis. Previous studies have shown an association between the FAS gene and tumorigenesis. In the present study, we evaluated the relationship between FAS A-670G (rs 1800682) and UL risk. Methods: The FAS gene polymorphism of...
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Genetic polymorphism of glutamate-cysteine ligase (GCL) could lead the changes in GCL enzyme activities. These changes could disrupt glutathione synthesis allowing the reduction of glutathione level. Furthermore, the decrease of glutathione level would change the phenotype and lead to the lack of defense against some diseases. The aim of this study was to determine the relationship between gene...
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Multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system is believed to have a T cell-mediated autoimmune etiology. The cytotoxic T lymphocyte antigen 4 (CTLA-4) gene is a strong candidate for the involvement in autoimmune diseases. To examine the genetic association of the CTLA-4 gene locus with MS, in a case-control design, we analyzed (-318 C/T) sin...
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ژورنال
عنوان ژورنال: Polish Journal of Pathology
سال: 2018
ISSN: 1233-9687
DOI: 10.5114/pjp.2018.81700